Pipeline

Macrophage-mediated diseases indications

Allocetra™ pipeline building momentum:
Strong phase 2 progress with next steps in sight

Indication:

Pre-clinical

Phase I/II

Phase II

Phase III

ENX-CL-05-001

Moderate knee
osteoarthritis

Administration:

Local knee injection

ClinicalTrials.gov ID

NCT06233474

A double blind, randomized, multi-center study to evaluate the safety and efficacy of intra-articular administration of Allocetra™ compared to placebo in patients with symptomatic knee osteoarthritis.

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1400-24-SMC

Temporomandibular joint
osteoarthritis

Administration:

Local TMJ injection

ClinicalTrials.gov ID

NCT06748651

A single center, Investigator-initiated study to evaluate the safety and initial efficacy of intra-articular administration of Allocetra™ to patients with Temporomandibular Joint Osteoarthritis (TMJ-OA).

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ENX-CL-02-002

Organ failure associated
with Sepsis

Administration:

Systemic administration

ClinicalTrials.gov ID

NCT04612413

A phase 2, multi-center, randomized, placebo-controlled, dose-finding study evaluating efficacy, safety and tolerability of different doses and regimens of Allocetra™ for the treatment of organ failure in adult sepsis patients.

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